Download SOT 2015 posters highlighting the Nuclear Receptor platform Applications.
Ren Houtman from PamGene, with collaborators from NCATS, NIH, Bethesda, MD, USA and Division of Toxicology, Wageningen University, Wageningen, Netherlands presented two very interesting posters at the Society of Toxicology's annual meeting, highlighting the potential of the unique Nuclear Receptor MARCoNI platform in Toxicology research.
René Houtman et al (abstract 2478) have suggested that FXR-coregulator interaction profiling provides a novel method to classify the mechanism of action for the structure related compounds.

Laura de Haan et al (abstract 2322) have shown that differences in modulation of the interaction of the ERs with coregulators by different (ant)agonists were more pronounced, enabling a qualitative discrimination between different agonists and antagonists for the same receptor.