Testing of kinase activity in a cell or tissue sample takes place on a PamChip® microarray, through detection and interpretation of phosphorylation patterns. Assays take place within a unique microscopic aluminium oxide matrix. The PamChip® is made in a 4 and 96 microarray (well) format.
In addition to the tyrosine kinase PamChip® array, other types of array have been developed for a range of other applications.
Tyrosine Kinase PamChip® Arrays
Description:
General Tyrosine Kinase chip containing 144 tyrosine kinase substrates
VEGF Tyrosine Kinase array containing substrates associated with VEGF pathways
Serine/Threonine PamChip® Arrays
Description:
Containing 144 serine and threonine kinase substrates
Nuclear Receptor PamChip® Arrays
Description:
Containing 53 coregulator peptides
PAM4U PamChip Microarrays for DNA Appplications
Description:
for analysis of SNP's and chromsome and exon copy number changes
each array contains up to 124 oligonucleotides in duplicate
each oligo sequence is complimentary to detection sequences on probes of your choice - giving you the ultimate in flexibility