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Brochures

  • PamGene and Kinases
  • Tyrosine Kinase PamChip® Arrays
  • Nuclear Receptors
  • Trisomy and SNP's
  • PamStation®12

Application Notes

Kinases
  • Assay Development for High Throughput Screening using PamChip® Microarrays
  • Simultaneous Potency Determination and Selectivity Profiling of Erb-B4 Kinase Inhibitors
  • Multiplex Kinase Assay for Selectivity Profiling and Potency Determination of Kinase Inhibitors
  • Detection of Tumour Cell Lysate Kinase Activity from Frozen Tissue Slices on PamChip® Microarrays

Gene Expression
  • Gene Expression Profiling of Heat Shock Genes on PamChip® Arrays

Mutation Detection
  • Efficient hybridisation of tagged mini-sequence reactions to PamChip® Microarrays enables rapid mutation detection
  • Detection of copy number changes in the BRCA1 gene using Multiplex Ligation-dependent Probe Amplification and PamChip® arrays

Genotyping
  • Real-time detection of sequence variation in Mycobacterium tuberculosis derived PCR products using PamChip® Microarays, for speciation and detection of rifampicin resistance.

Posters

  • Nuclear Receptor/Compound Interaction studies using Flow-Through Microarrays (carried out in collaboration with Merck & Co)
  • Evaluation of PamGene's PamChip® Kinase Assay: a Potential Platform for Biomarker Discovery (carried out in collaboration with Wyeth)
  • Array-based screening of subtelomeric chromosome 1 copy number changes using PamChip® technology
  • Detection of Trisomy Syndromes in Clinical Genetics on PamChip® Arrays; a 6-hour Assay
  • Use of flow-through peptide microarrays in cell-lysates: comparison of lysates from clinical brain tissues on tyrosine phosphorylation cell-signaling arrays